Evolution of Diagnostic Criteria for Gestational Diabetes Mellitus and Risk Factors of Progression to Postpartum Type 2 Diabetes from Gestational Diabetes Mellitus
Baixue Lv, Bin Jiang, Xuemei Wang

Gestational diabetes mellitus (GDM) is defined as diabetes diagnosed in the second or third trimester of pregnancy that is not type 1 or type 2 diabetes mellitus (T1DM or T2DM). There are many different GDM diagnostic criteria in clinical use. However, regardless of which diagnostic criteria are used, it has been shown that women with GDM are at increased risk for postpartum T2DM and that, among women with T2DM, as many as one third of women have experienced a pregnancy of GDM. Various risk factors for postpartum T2DM have been identified, including body weight/ body mass index of pre-pregnancy and postpartum, gestational age at diagnosis, ethnicity, and family history of diabetes, genetic risk factors and breastfeeding etc. This paper reviews diagnostic criteria for GDM established by different organizations and summarizes the findings of the incidence and risk factors of postpartum T2DM and the recent lifestyle interventional trials that aimed to prevent postpartum T2DM in women with a history of GDM

Full Text: PDF     DOI: 10.15640/aijb.v5n2a1